Bioactive Small Molecules
Medchemexpress LLC 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride | 90384-82-0 | 99.0% | C44H28ClFeN4O12S4 | 10MG
FeTPPS (5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrin iron(III) chloride) is an iron porphyrin reagent used in biochemical research as a peroxynitrite scavenger and decomposition catalyst. It is provided as a high-purity compound for in vitro studies, nitration inhibition experiments, and mechanistic investigations of reactive nitrogen species.
- High purity (99.0%) suitable for research use.
- Functions as a peroxynitrite scavenger and anti-nitrating agent.
- Aids studies of reactive nitrogen species and oxidative stress pathways.
- Water-soluble sulfonated porphyrin scaffold for biochemical assays.
- Available in multiple small-mass package sizes for lab-scale experiments.
Selleck Chemical LLC Benzylamiloride hydrochloride S0406-5MG
Benzylamiloride hydrochloride (Benzamil hydrochloride) is an inhibitor of Na /Ca2 exchanger (NCX) with an IC50 100 nM It reduces hyponatremic brain edema by blocking sodium influx in vivo
Cayman Chemical BAY 57-1293 25mg
An orally bioavailable helicase-primase inhibitor; inhibits the ATPase activity of HSV helicase-primase (IC50 = 30 nM); inhibits HSV replication in Vero cells (IC50 = 20 nM for both HSV-1 and HSV-2); active against porcine and bovine HSV strains (IC50s = 5 and 0.12 μM, respectively); effective against HSV-1 and HSV-2 in a lethal challenge model (ED50 = 0.5 mg/kg in mice and rats) and in a zosteriform spread model, at a dose of 15 mg/kg, in mice and Lewis rats; reduces levels of Aβ and phosphorylated Tau production in HSV-1 infected Vero cells
Medchemexpress LLC Sarecycline hydrochloride | 1035979-44-2 | 99.8% | 523.96 | 1 ML
Sarecycline hydrochloride is an orally active, narrow-spectrum tetracycline derivative antibiotic with anti-inflammatory properties. It is known to inhibit Gram-positive bacteria and several types of *keratobacterium acnes*. Its mechanism of action involves interfering with tRNA accommodation and tethering mRNA to the 70S ribosome. This compound is used in research to study moderate to severe acne.
- Orally active
- Narrow-spectrum antibiotic
- Anti-inflammatory activity
- Mechanism of action involves interfering with tRNA accommodation and tethering mRNA to the 70S ribosome
- Used for studying moderate to severe acne
Selleck Chemical LLC Isorhychophylline S9310-1MG
Isorhynchophylline (IsoRhy 7-Isorhyncophylline) is a major tetracyclic oxindole alkaloid isolated from the Chinese herbal medicine Uncaria rhynchophylla (Miq )Jacks (Gouteng in Chinese) It acts as a neuronal autophagy inducer with therapeutic potential for cardiovascular and central nervous system diseases
Selleck Chemical LLC JNJ-38877618 S8854-5MG
JNJ-38877618 (OMO-1) is a potent highly selective orally bioavailable Met (c-Met) kinase inhibitor with binding affinity (Kd) of 1 4 nM and enzyme inhibitory activity against wt and M1268T mutant Met (c-Met) (2 and 3 nM IC50)
AdipoGen Gitoxin (5 mg)
Chemical. CAS: 4562-36-1. Formula: C41H64O14. MW: 780.9. Isolated from Digitalis purpurea L. Cardiac glycoside. Natural metabolite of digitoxin. Starting material for the synthesis of gitoxin derivatives with activity as cardiac glycosides. Uncompetitive inhibitor of the Na+/K+ ATPase activity. Inhibits growth of selected human cancer cells.
Cayman Chemical ANTIBODY L-838 417 5mg
A partial agonist of α2-, α3-, and α5 subunit-containing GABAA receptors; potentiates GABA-induced currents in LTK- cells expressing α2β3γ2, α3β3γ2, or α5β3γ2 subunit-containing GABAA receptors at 100 nM; increases the mechanical paw withdrawal threshold in a rat model of spinal nerve ligation-induced static allodynia at 10 mg/kg; decreases social avoidance in a novel environment in adult and adolescent rats at 1 and 2 mg/kg, respectively
Cayman Chemical ANTIBODY DMPAC-Chol 5mg
A cationic cholesterol derivative; has been used in liposome formation for gene transfection; a component of liposomes that bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA at lipsome:DNA ratios from 2.5:1-10:1 w/w; reduces viability of HepG2 cells by 63% when used in liposomes at 37.5 UG/ml
Medchemexpress LLC Animal-Free IP-10/CX 50ug
The IP-10/CRG-2/CXCL10 protein is a pro-inflammatory cytokine involved in a variety of biological processes including chemotaxis immune cell activation growth regulation apoptosis and vasostatic regulation During viral infection IP-10 crucially stimulates immune cell activation and migration to the site of infection Animal-Free IP-10/CXCL10 Protein Human (His) is the recombinant human-derived animal-FreeIP-10/CRG-2/CXCL10 protein expressed by E coli with N-His labeled tag This product is for cell culture use only
Selleck Chemical LLC Lithospermoside S9073-1MG
Lithospermoside (Griffonin) extracted from the roots of Lithospermum purpurocaeruleum and L officinale (Borginaceae) and Thalictrum rugosum and T dasycarpum (Ranunculaceae) has anti-oxidant anti-tumor promoting activities
Medchemexpress LLC HY-139504 5mg , CC-99677 CAS:1887069-10-4 Purity:>98%
HY-139504 5mg CC-99677 CAS: 1887069-10-4 CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). CC-99677 is extracted from patent WO2020236636, compound 1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 4-nitrophenyl 2-(3-methoxypropyl)piperidine-1-carboxylate | 1338575-28-2 | 99.5% | 50MG
4-nitrophenyl 2-(3-methoxypropyl)piperidine-1-carboxylate | 1338575-28-2 | 99.5% | 50MG
