Bioactive Small Molecules
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Filtered Search Results
Selleck Chemical LLC MYCi975 S8906-10MM/1ML
MYCi975 (NUCC-0200975) is a potent selective and orally active inhibitor of MYC that disrupts MYC/MAX interaction promotes MYC T58 phosphorylation and MYC degradation and impairs MYC driven gene expression MYCi975 exhibits potent anti-tumor activities
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Selleck Chemical LLC Saruparib S9875-25MG
Saruparib (AZD5305) is a highly selective and potent inhibitor of PARP1 with an IC50 of 3 nM in wild-type A549 lung cancer cells AZD5305 shows no or minimal growth inhibitory effects in other cells (IC50s 10 M)
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Selleck Chemical LLC Orforglipron S9852-25MG
Orforglipron(LY3502970) is a non-peptidal agonist of glucagon-like peptide 1(GLP-1) receptor It can be used efficiently in glycemic control and weight reduction in type 2 diabetes mellitus (T2DM) obesity or both
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Cell Signaling Technology Vorinostat (SAHA), HDAC Inhibitor, >99% Purity, 5 mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Vorinostat (SAHA) is a histone deacetylase (HDAC) inhibitor that functions by binding to and blocking the active site of the enzyme. It inhibits both class I and class II HDACs at nanomolar concentrations, leading to the accumulation of acetylated histones and other proteins that regulate gene expression. This activity can induce cell cycle arrest, differentiation, or apoptosis in transformed cell types.
- Inhibits class I and class II HDACs
- Induces cell cycle arrest and apoptosis
- Supplied as a lyophilized powder
- Purity >99%
- Molecular weight 264.32 g/mol
- Soluble in DMSO at 66 mg/mL and ethanol at 2 mg/mL
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Helenalin, 500UG, PURITY 98.87%
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Helenalin, 500UG, PURITY 98.87%
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Medchemexpress LLC Sjg-136 1Mg | HY14573-1MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Sjg-136 1Mg
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MOLECULAR DEPOT LLC Citrate Synthase - 200 U
Citrate Synthase from Porcine Heart consists of a native Citrate Synthase purified from Porcine Heart This enzyme catalyzes the conversion of citrate to acetyl-CoA in the presence of coenzyme-A This product has been used as molecular tool for various biochemical applications It has also been used in a wide array of other chemical and immunological applications For in vitro research use only
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Selleck Chemical LLC PF-06873600 S8816-5MG
PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (CDK2) CDK4 and CDK6 with Ki values of 0 1 1 2 and 0 1 nM respectively blocks the phosphorylation of retinoblastoma protein (RB1) and limits the proliferation of OVCAR-3 ovarian cancer cells with EC50s of 19 and 45 nM respectively
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Selleck Chemical LLC Sotorasib S8830-10MM/1ML
Sotorasib (AMG510) is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity This AMG510 is a chiral compound
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Biotium CYANINE 647 ALKYNE 1MG
CYANINE 647 ALKYNE 1MG
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Cayman Chemical Bilirubin, Purity: ≥95%, CAS: 635-65-4, 1 g
A yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase; has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions
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Selleck Chemical LLC Palmitic acid 25mg
Palmitic acid (Hexadecanoic acid, Cetylic acid) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Pilocarpine HCl 50mg
Pilocarpine HCl (NSC 5746) is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Thapsigargin 1mg
Thapsigargin is a potent, non-competitive inhibitor ofthe sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50 of 0.353 nM or 0.448 nM for the carbachol-evoked [Ca2+]i-transients with or without a KCl-prestimulation. Thapsigargin induces cellapoptosis. Thapsigargin is extracted from a plant, Thapsia garganica. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC AOA hemihydrochloride 25mg
AOA hemihydrochloride (Aminooxyacetic acid, Carboxymethoxylamine, AOAA, Aminooxyacetate hemihydrochloride) is an inhibitor ofaminobutyrate aminotransferase involved in amino acid and polyamine metabolism. AOA hemihydrochloride is also aCBS (cystathionine ?-synthase) inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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